In a recent case of antibiotic resistance, a 70 year old woman from Nevada, USA succumbed to the infection as she was suffering from Klibsiella Pneumonia. The lady was resistant to 26 different antibiotics and finally died due to multiple organ failure. During her visit to India, she was hospitalised to different hospitals in India before she returned to her native place. In Nevada USA she was hospitalised and given private room and she remained isolated from other patients. It is still a matter of research why and how she developed Antibiotic resistance. This is not the only case where patient becoming resistant to drugs. There are several other cases particularly seen and heard commonly in Tuberculosis patient. The worsen form of tuberculosis infection is called MDR-TB meaning Multi Drug Resistant TB. There are many incidence reported where patient already affected with tuberculosis shows no improvement and become resistant to most important ist line drug of tuberculosis. Those drugs are Isoniazid & Rifampicin. In another form of MDR-TB, which is its severe type, patient becomes resistant to one more drug i.e, Fluoroquinolone and at least one of the three second line drug (Kanamycin, Capreomycin & Amikacin). This form of MDR-TB is hence called XDR-TB, meaning Xtreme Drug Resistant TB.
Short note on Superbug
The term Superbug refers for the strain of bacteria that are resistant to Several types of antibiotics. Mutations in bacterial genome can result can create strain of bacteria which shows no effect of antibiotics on them. Superbug is the result of over prescription and Overuse of the medicines.
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